Tlr4/md-2 is a receptor for extracellular nucleophosmin 1

by Kota Nakatomi, Hikari Ueno, Yuto Ishikawa, Ronny Christiadi Salim, Yuki Mori, Issey Kanemoto, Salunya Tancharoen, Kiyoshi Kikuchi, Naoki Miura, Taketo Omori, Emiko Okuda-Ashitaka, Kiyoshi Matsumura, Hitoshi Imaizumi, Yoshihiro Motomiya, Ikuro Maruyama, Ko Ichi Kawahara
Published 2021

Secondary prevention of stroke: Pleiotropic effects of optimal oral pharmacotherapy (review)

by Kiyoshi Kikuchi, Ko Ichi Kawahara, Naoki Miura, Takashi Ito, Yoko Morimoto, Salunya Tancharoen, Nobuyuki Takeshige, Hisaaki Uchikado, Rokudai Sakamoto, Naohisa Miyagi, Chiemi Kikuchi, Narumi Iida, Naoto Shiomi, Terukazu Kuramoto, Masaru Hirohata, Ikuro Maruyama, Motohiro Morioka, Eiichiro Tanaka
Published 2018

E8002 inhibits peripheral nerve adhesion by enhancing fibrinolysis of l-ascorbic acid in a rat sciatic nerve model

by Kiyoshi Kikuchi, Kentaro Setoyama, Seiya Takada, Shotaro Otsuka, Kazuki Nakanishi, Kosuke Norimatsu, Akira Tani, Harutoshi Sakakima, Ko Ichi Kawahara, Kazuya Hosokawa, Ryoji Kiyama, Megumi Sumizono, Salunya Tancharoen, Ikuro Maruyama, Gohsuke Hattori, Motohiro Morioka, Eiichiro Tanaka, Hisaaki Uchikado
Published 2020

Uric acid enhances alteplase-mediated thrombolysis as an antioxidant

by Kiyoshi Kikuchi, Kentaro Setoyama, Eiichiro Tanaka, Shotaro Otsuka, Takuto Terashi, Kazuki Nakanishi, Seiya Takada, Harutoshi Sakakima, Sumate Ampawong, Ko ichi Kawahara, Tomoka Nagasato, Kazuya Hosokawa, Yoichiro Harada, Mika Yamamoto, Chinatsu Kamikokuryo, Ryoji Kiyama, Motohiro Morioka, Takashi Ito, Ikuro Maruyama, Salunya Tancharoen
Published 2019

Mechanism of HMGB1 release inhibition from RAW264.7 cells by oleanolic acid in Prunus mume Sieb. et Zucc

by Ko Ichi Kawahara, Teruto Hashiguchi, Kazuo Masuda, Abbi R. Saniabadi, Kiyoshi Kikuchi, Salunya Tancharoen, Takashi Ito, Naoki Miura, Yoko Morimoto, Kamal K. Biswas, Yuko Nawa, Xiaojie Meng, Yoko Oyama, Kazunori Takenouchi, Binita Shrestha, Hisayo Sameshima, Toshiaki Shimizu, Taro Adachi, Masakazu Adachi, Ikuro Maruyama
Published 2018

The free radical scavenger edaravone rescues rats from cerebral infarction by attenuating the release of high-mobility group box-1 in neuronal cells

by Kiyoshi Kikuchi, Ko Ichi Kawahara, Salunya Tancharoen, Fumiyo Matsuda, Yoko Morimoto, Takashi Ito, Kamal Krishna Biswas, Kazunori Takenouchi, Naoki Miura, Yoko Oyama, Yuko Nawa, Noboru Arimura, Masahiro Iwata, Yutaka Tajima, Terukazu Kuramoto, Kenji Nakayama, Minoru Shigemori, Yoshihiro Yoshida, Teruto Hashiguchi, Ikuro Maruyama
Published 2018

Edaravone: A new therapeutic approach for the treatment of acute stroke

by Kiyoshi Kikuchi, Ko Ichi Kawahara, Naohisa Miyagi, Hisaaki Uchikado, Terukazu Kuramoto, Yoko Morimoto, Salunya Tancharoen, Naoki Miura, Kazunori Takenouchi, Yoko Oyama, Binita Shrestha, Fumiyo Matsuda, Yoshihiro Yoshida, Shinichiro Arimura, Kentaro Mera, Ko Ichi Tada, Narimasa Yoshinaga, Ryuichi Maenosono, Yoshiko Ohno, Teruto Hashiguchi, Ikuro Maruyama, Minoru Shigemori
Published 2018

Edaravone, a synthetic free radical scavenger, enhances alteplase-mediated thrombolysis

by Kiyoshi Kikuchi, Kentaro Setoyama, Ko Ichi Kawahara, Tomoka Nagasato, Takuto Terashi, Koki Ueda, Kazuki Nakanishi, Shotaro Otsuka, Naoki Miura, Hisayo Sameshima, Kazuya Hosokawa, Yoichiro Harada, Binita Shrestha, Mika Yamamoto, Yoko Morimoto-Yamashita, Haruna Kikuchi, Ryoji Kiyama, Chinatsu Kamikokuryo, Salunya Tancharoen, Harutoshi Sakakima, Motohiro Morioka, Eiichiro Tanaka, Takashi Ito, Ikuro Maruyama
Published 2018

Potential of edaravone for neuroprotection in neurologic diseases that do not involve cerebral infarction (Review)

by Kiyoshi Kikuchi, Ko Ichi Kawahara, Hisaaki Uchikado, Naohisa Miyagi, Terukazu Kuramoto, Tomoya Miyagi, Yoko Morimoto, Takashi Ito, Salunya Tancharoen, Naoki Miura, Kazunori Takenouchi, Yoko Oyama, Binita Shrestha, Fumiyo Matsuda, Yoshihiro Yoshida, Shinihiro Arimura, Kentaro Mera, Ko Ichi Tada, Narimasa Yoshinaga, Ryuichi Maenosono, Yoshiko Ohno, Teruto Hashiguchi, Ikuro Maruyama, Minoru Shigemori
Published 2018

C-reactive protein induces high-mobility group box-1 protein release through activation of p38MAPK in macrophage RAW264.7 cells

by Ko ichi Kawahara, Kamal Krishna Biswas, Masako Unoshima, Takashi Ito, Kiyoshi Kikuchi, Yoko Morimoto, Masahiro Iwata, Salunya Tancharoen, Yoko Oyama, Kazunori Takenouchi, Yuko Nawa, Noboru Arimura, Meng Xiao Jie, Binita Shrestha, Naoki Miura, Toshiaki Shimizu, Kentaro Mera, Shin ichiro Arimura, Noboru Taniguchi, Hideo Iwasaka, Sonshin Takao, Teruto Hashiguchi, Ikuro Maruyama
Published 2018

Edaravone attenuates cerebral ischemic injury by suppressing aquaporin-4

by Kiyoshi Kikuchi, Salunya Tancharoen, Fumiyo Matsuda, Kamal Krishna Biswas, Takashi Ito, Yoko Morimoto, Yoko Oyama, Kazunori Takenouchi, Naoki Miura, Noboru Arimura, Yuko Nawa, Xiaojie Meng, Binita Shrestha, Shinichiro Arimura, Masahiro Iwata, Kentaro Mera, Hisayo Sameshima, Yoshiko Ohno, Ryuichi Maenosono, Yutaka Tajima, Hisaaki Uchikado, Terukazu Kuramoto, Kenji Nakayama, Minoru Shigemori, Yoshihiro Yoshida, Teruto Hashiguchi, Ikuro Maruyama, Ko ichi Kawahara
Published 2018

Minocycline attenuates both OGD-induced HMGB1 release and HMGB1-induced cell death in ischemic neuronal injury in PC12 cells

by Kiyoshi Kikuchi, Ko ichi Kawahara, Kamal Krishna Biswas, Takashi Ito, Salunya Tancharoen, Yoko Morimoto, Fumiyo Matsuda, Yoko Oyama, Kazunori Takenouchi, Naoki Miura, Noboru Arimura, Yuko Nawa, Xiaojie Meng, Binita Shrestha, Shinichiro Arimura, Masahiro Iwata, Kentaro Mera, Hisayo Sameshima, Yoshiko Ohno, Ryuichi Maenosono, Yoshihiro Yoshida, Yutaka Tajima, Hisaaki Uchikado, Terukazu Kuramoto, Kenji Nakayama, Minoru Shigemori, Teruto Hashiguchi, Ikuro Maruyama
Published 2018

HMGB1: A new marker for estimation of the postmortem interval

by Kiyoshi Kikuchi, Ko ichi Kawahara, Kamal Krishna Biswas, Takashi Ito, Salunya Tancharoen, Naoto Shiomi, Yoshiro Koda, Fumiyo Matsuda, Yoko Morimoto, Yoko Oyama, Kazunori Takenouchi, Naoki Miura, Noboru Arimura, Yuko Nawa, Shinichiro Arimura, Meng Xiao Jie, Binita Shrestha, Masahiro Iwata, Kentaro Mera, Hisayo Sameshima, Yoshiko Ohno, Ryuichi Maenosono, Yutaka Tajima, Hisaaki Uchikado, Terukazu Kuramoto, Kenji Nakayama, Minoru Shigemori, Yoshihiro Yoshida, Teruto Hashiguchi, Ikuro Maruyama
Published 2018