A novel F420-dependent anti-oxidant mechanism protects Mycobacterium tuberculosis against oxidative stress and bactericidal agents

由 Gurumurthy, M., Rao, M., Mukherjee, T., Rao, S.P.S., Boshoff, H.I., Dick, T., Barry, C.E., Manjunatha, U.H.
出版 2014

Substrate specificity of the deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis responsible for the bioreductive activation of bicyclic nitroimidazoles

由 Gurumurthy, M., Mukherjee, T., Dowd, C.S., Singh, R., Niyomrattanakit, P., Tay, J.A., Nayyar, A., Lee, Y.S., Cherian, J., Boshoff, H.I., Dick, T., Barry III, C.E., Manjunatha, U.H.
出版 2014

Pharmacokinetics-pharmacodynamics analysis of bicyclic 4-nitroimidazole analogs in a murine model of tuberculosis

由 Lakshminarayana S.B., Boshoff H.I.M., Cherian J., Ravindran S., Goh A., Jiricek J., Nanjundappa M., Nayyar A., Gurumurthy M., Singh R., Dick T., Blasco F., Barry III C.E., Ho P.C., Manjunatha U.H.
出版 2018

Indolcarboxamide is a preclinical candidate for treating multidrug-resistant tuberculosis

由 Rao, S.P.S., Lakshminarayana, S.B., Kondreddi, R.R., Herve, M., Camacho, L.R., Bifani, P., Kalapala, S.K., Jiricek, J., Ma, N.L., Tan, B.H., Ng, S.H., Nanjundappa, M., Ravindran, S., Seah, P.G., Thayalan, P., Lim, S.H., Lee, B.H., Goh, A., Barnes, W.S., Chen, Z., Gagaring, K., Chatterjee, A.K., Pethe, K., Kuhen, K., Walker, J., Feng, G., Babu, S., Zhang, L., Blasco, F., Beer, D., Weaver, M., Dartois, V., Glynne, R., Dick, T., Smith, P.W., Diagana, T.T., Manjunatha, U.H.
出版 2016