Intrauterine gene transfer at early gestation with safe postnatal vector re-administration: a therapeutic strategy for early-onset congenital disease

by Citra Nurfarah Zaini Mattar, Chan, Jerry KY, Biswas, Arijit, Choolani, Mahesh, Nathwani, Amit
Published 2019

A SHORT INVESTIGATION OF MIXED HAEMATOPOIETIC CHIMERISM: AN NHP MODEL OF INTRAUTERINE HAEMATOPOIETIC STEM CELL TRANSPLANTATION (IUHSCT)

by Citra Nurfarah Zaini Mattar, Chan, Jerry KY, Biswas, Arijit, Choolani, Mahesh, Nathwani, Amit
Published 2019

Immunological response to AAV-IUGT administered in early gestation in a non-human primate model

by CITRA NURFARAH ZAINI MATTAR, Johana, Nuryanti, Nathwani, Amit, BISWAS,ARIJIT, CHOOLANI,MAHESH A, JERRY CHAN KOK YEN
Published 2019

Correction of Murine Diabetic Hyperglycaemia With A Single Systemic Administration of An AAV2/8 Vector Containing A Novel Codon Optimized Human Insulin Gene

by Uin, Gan Shu, Maria, Notaridou, Ying, Fu Zhen, Onn, Lee Kok, Chuan, Sia Kian, Chunilal, Nathwani Amit, Marco, Della Peruta, Yorke, Calne Roy
Published 2021

Immunosuppression overcomes insulin- and vector-specific immune responses that limit efficacy of AAV2/8-mediated insulin gene therapy in NOD mice

by Recino, Asha, Gan, Shu Uin, Sia, Kian Chuan, Sawyer, Yvonne, Trendell, Jenny, Kay, Richard, Gribble, Fiona M, Reimann, Frank, Foale, Rob, Notaridou, Maria, Holmes, Nick, Lever, Andrew, Lee, Kok Onn, Nathwani, Amit, Cooke, Anne, Calne, Roy, Wallberg, Maja
Published 2021