Substrate specificity of the deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis responsible for the bioreductive activation of bicyclic nitroimidazoles

by Gurumurthy, M., Mukherjee, T., Dowd, C.S., Singh, R., Niyomrattanakit, P., Tay, J.A., Nayyar, A., Lee, Y.S., Cherian, J., Boshoff, H.I., Dick, T., Barry III, C.E., Manjunatha, U.H.
Published 2014

NOS2-deficient mice with hypoxic necrotizing lung lesions predict outcomes of tuberculosis chemotherapy in humans

by Gengenbacher, M, Duque-Correa, M.A, Kaiser, P, Schuerer, S, Lazar, D, Zedler, U, Reece, S.T, Nayyar, A, Cole, S.T, Makarov, V, Barry, C.E, Dartois, V, Kaufmann, S.H.E
Published 2020

Pharmacokinetics-pharmacodynamics analysis of bicyclic 4-nitroimidazole analogs in a murine model of tuberculosis

by Lakshminarayana S.B., Boshoff H.I.M., Cherian J., Ravindran S., Goh A., Jiricek J., Nanjundappa M., Nayyar A., Gurumurthy M., Singh R., Dick T., Blasco F., Barry III C.E., Ho P.C., Manjunatha U.H.
Published 2018