Substrate specificity of the deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis responsible for the bioreductive activation of bicyclic nitroimidazoles

由 Gurumurthy, M., Mukherjee, T., Dowd, C.S., Singh, R., Niyomrattanakit, P., Tay, J.A., Nayyar, A., Lee, Y.S., Cherian, J., Boshoff, H.I., Dick, T., Barry III, C.E., Manjunatha, U.H.
出版 2014

NOS2-deficient mice with hypoxic necrotizing lung lesions predict outcomes of tuberculosis chemotherapy in humans

由 Gengenbacher, M, Duque-Correa, M.A, Kaiser, P, Schuerer, S, Lazar, D, Zedler, U, Reece, S.T, Nayyar, A, Cole, S.T, Makarov, V, Barry, C.E, Dartois, V, Kaufmann, S.H.E
出版 2020

Pharmacokinetics-pharmacodynamics analysis of bicyclic 4-nitroimidazole analogs in a murine model of tuberculosis

由 Lakshminarayana S.B., Boshoff H.I.M., Cherian J., Ravindran S., Goh A., Jiricek J., Nanjundappa M., Nayyar A., Gurumurthy M., Singh R., Dick T., Blasco F., Barry III C.E., Ho P.C., Manjunatha U.H.
出版 2018