Fused in sarcoma (FUS) protein lacking nuclear localization signal (NLS) and major RNA binding motifs triggers proteinopathy and severe motor phenotype in transgenic mice

بواسطة Shelkovnikova, T.A, Peters, O.M, Deykin, A.V, Connor-Robson, N, Robinson, H, Ustyugov, A.A, Bachurin, S.O, Ermolkevich, T.G, Goldman, I.L, Sadchikova, E.R, Kovrazhkina, E.A, Skvortsova, V.I, Ling, S.-C, Da Cruz, S, Parone, P.A, Buchman, V.L, Ninkina, N.N
منشور في 2020

Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis

بواسطة Ling, S.-C., Dastidar, S.G., Tokunaga, S., Ho, W.Y., Lim, K., Ilieva, H., Parone, P.A., Tyan, S.-H., Tse, T.M., Chang, J.-C., Platoshyn, O., Bui, N.B., Bui, A., Vetto, A., Sun, S., McAlonis-Downes, M., Han, J.S., Swing, D., Kapeli, K., Yeo, G.W., Tessarollo, L., Marsala, M., Shaw, C.E., Tucker-Kellogg, G., La Spada, A.R., Lagier-Tourenne, C., Da Cruz, S., Cleveland, D.W.
منشور في 2021