PENGARUH EKSTRAK BATANG PISANG AMBON (Musa paradisiaca var. sapientum) TERHADAP GAMBARAN HISTOPATOLOGI JEJUNUM TIKUS (Rattus norvegicus) INFLAMMATORY BOWEL DISEASE
This research aimed to study the effect of Ambon banana hump (Musa paradisiaca var. sapientum) extract to prevent destruction on jejunum, and as well as observe the difference of histopathology of indomethacine induced rat (Rattus norvegicus) in jejunum. This research used about 30 male rats 8 –...
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id-langga.559542017-04-05T02:19:00Z http://repository.unair.ac.id/55954/ PENGARUH EKSTRAK BATANG PISANG AMBON (Musa paradisiaca var. sapientum) TERHADAP GAMBARAN HISTOPATOLOGI JEJUNUM TIKUS (Rattus norvegicus) INFLAMMATORY BOWEL DISEASE RADITYA DIMAS PRAYOGA, 061211131065 SF405.5-407 Laboratory animals This research aimed to study the effect of Ambon banana hump (Musa paradisiaca var. sapientum) extract to prevent destruction on jejunum, and as well as observe the difference of histopathology of indomethacine induced rat (Rattus norvegicus) in jejunum. This research used about 30 male rats 8 – 12 week, with average weight 150 gram. They were randomly selected and devided into 5 groups. K(-) was given 0,5 ml CMC Na 0,5% for 9 days and 0,5 ml corn oil was given on day 10. K(+) was given 0,5 ml CMC Na 0,5% for 9 days and then was induce by 30 mg/kg BW indomethacine once tim eon day 10. P1, P2, P3 were given ambon banana hump extract (P1: 20 mg/150 g BW, P2: 40 mg/150 g BW, P3: 80 mg/150 g BW) after that, were induced by 30 mg/kg BW Indomethacine once time on day 10. Each jejunum spesimen was processed and the histopathological changes were observed. Score of submucosal edema and epithelial integrity as qualitative data were analyzed with Kruskal Wallis test continued by Mann-Whitney test. The result were 1) ambon banana hump extract was not significant in reducing jejunum submucosal edema induced by indomethacine, 2) ambon banana hump extract was not significant in reducing jejunum epithelial integrity induced by indomethacine. 2016 Thesis NonPeerReviewed text id http://repository.unair.ac.id/55954/1/KH%20114-16%20Pra%20p%20ABSTRAK.pdf text id http://repository.unair.ac.id/55954/2/KH%20114-16%20Pra%20p%20SKRIPSI.pdf RADITYA DIMAS PRAYOGA, 061211131065 (2016) PENGARUH EKSTRAK BATANG PISANG AMBON (Musa paradisiaca var. sapientum) TERHADAP GAMBARAN HISTOPATOLOGI JEJUNUM TIKUS (Rattus norvegicus) INFLAMMATORY BOWEL DISEASE. Skripsi thesis, Universitas Airlangga. http://lib.unair.ac.id |
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SF405.5-407 Laboratory animals RADITYA DIMAS PRAYOGA, 061211131065 PENGARUH EKSTRAK BATANG PISANG AMBON (Musa paradisiaca var. sapientum) TERHADAP GAMBARAN HISTOPATOLOGI JEJUNUM TIKUS (Rattus norvegicus) INFLAMMATORY BOWEL DISEASE |
description |
This research aimed to study the effect of Ambon banana hump (Musa
paradisiaca var. sapientum) extract to prevent destruction on jejunum, and
as well as observe the difference of histopathology of indomethacine
induced rat (Rattus norvegicus) in jejunum. This research used about 30
male rats 8 – 12 week, with average weight 150 gram. They were randomly
selected and devided into 5 groups. K(-) was given 0,5 ml CMC Na 0,5%
for 9 days and 0,5 ml corn oil was given on day 10. K(+) was given 0,5 ml
CMC Na 0,5% for 9 days and then was induce by 30 mg/kg BW
indomethacine once tim eon day 10. P1, P2, P3 were given ambon banana
hump extract (P1: 20 mg/150 g BW, P2: 40 mg/150 g BW, P3: 80 mg/150 g
BW) after that, were induced by 30 mg/kg BW Indomethacine once time on
day 10. Each jejunum spesimen was processed and the histopathological
changes were observed. Score of submucosal edema and epithelial integrity
as qualitative data were analyzed with Kruskal Wallis test continued by
Mann-Whitney test. The result were 1) ambon banana hump extract was not
significant in reducing jejunum submucosal edema induced by
indomethacine, 2) ambon banana hump extract was not significant in
reducing jejunum epithelial integrity induced by indomethacine. |
format |
Theses and Dissertations NonPeerReviewed |
author |
RADITYA DIMAS PRAYOGA, 061211131065 |
author_facet |
RADITYA DIMAS PRAYOGA, 061211131065 |
author_sort |
RADITYA DIMAS PRAYOGA, 061211131065 |
title |
PENGARUH EKSTRAK BATANG PISANG AMBON
(Musa paradisiaca var. sapientum) TERHADAP
GAMBARAN HISTOPATOLOGI JEJUNUM TIKUS
(Rattus norvegicus) INFLAMMATORY BOWEL DISEASE |
title_short |
PENGARUH EKSTRAK BATANG PISANG AMBON
(Musa paradisiaca var. sapientum) TERHADAP
GAMBARAN HISTOPATOLOGI JEJUNUM TIKUS
(Rattus norvegicus) INFLAMMATORY BOWEL DISEASE |
title_full |
PENGARUH EKSTRAK BATANG PISANG AMBON
(Musa paradisiaca var. sapientum) TERHADAP
GAMBARAN HISTOPATOLOGI JEJUNUM TIKUS
(Rattus norvegicus) INFLAMMATORY BOWEL DISEASE |
title_fullStr |
PENGARUH EKSTRAK BATANG PISANG AMBON
(Musa paradisiaca var. sapientum) TERHADAP
GAMBARAN HISTOPATOLOGI JEJUNUM TIKUS
(Rattus norvegicus) INFLAMMATORY BOWEL DISEASE |
title_full_unstemmed |
PENGARUH EKSTRAK BATANG PISANG AMBON
(Musa paradisiaca var. sapientum) TERHADAP
GAMBARAN HISTOPATOLOGI JEJUNUM TIKUS
(Rattus norvegicus) INFLAMMATORY BOWEL DISEASE |
title_sort |
pengaruh ekstrak batang pisang ambon
(musa paradisiaca var. sapientum) terhadap
gambaran histopatologi jejunum tikus
(rattus norvegicus) inflammatory bowel disease |
publishDate |
2016 |
url |
http://repository.unair.ac.id/55954/1/KH%20114-16%20Pra%20p%20ABSTRAK.pdf http://repository.unair.ac.id/55954/2/KH%20114-16%20Pra%20p%20SKRIPSI.pdf http://repository.unair.ac.id/55954/ http://lib.unair.ac.id |
_version_ |
1681147322764886016 |