Antimalarial and antioxidant activity of phenolic compounds isolated from Erythrina crista-galli L.

• Main Authors: Tjahjandarie, Tjitjik Srie, Pudjiastuti, Pratiwi, Saputri, Ratih Dewi, Tanjung, Mulyadi
• Format: Article PeerReviewed
• Language: English; English; English
• Published: Journal of Chemical And Pharmaceutical Reseach 3/668 Ma;viya Nagar, Jalpur Rajasthan, India-3020I7 2014
• Subjects: QD Chemistry
• Online Access: http://repository.unair.ac.id/63035/1/Cover.pdf; http://repository.unair.ac.id/63035/2/Bukti%20C05.%20Antimalarial%20and%20antioxidant%20activity%20of%20phenolic%20compounds%20isolated.pdf; http://repository.unair.ac.id/63035/3/Bukti%20C05%20Peer%20reviewer%20dan%20validasi%20Kadep.pdf; http://repository.unair.ac.id/63035/; http://www.jocpr.com/
• Institution: Universitas Airlangga

Threephenolic compounds, phaseollidin (1), sandwicensin (2), and lonchocarpol A (3) had been isolated from the stem bark of Erythrina crista-galli. Their structures were established on the basis of spectroscopic evidence. Compounds 1–3 were evaluated for their antimalarial properties against Plasmodium palcifarum, showing their IC were 1.66, 1.83, and 1.69 µg/mL.The antioxidant activity of 1–3 against 2,2-diphenyl-1-picrylhydrazyl (DPPH), showing their IC50 were 209.4,305.6,and 1115.7 µM, respectively.