HUBUNGAN DERAJAT RASA HAUS DENGAN FRAKSI EJEKSI DAN KADAR NATRIUM PLASMA PADA GAGAL JANTUNG KRONIS USIA LANJUT

Thirst is a common symptom and disturbing for patient with heart failure. Many elderly patients with heart failure get severe thirst. Natural history of heart failure, pharmacologycal and non-pharmacologycal therapies could increase the thirst level. Low cardiac output and activation of neuro-hormon...

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Bibliographic Details
Main Authors: , dr. Sri Lestari, , dr. I Dewa Putu Pramantara, SpPD-KGer
Format: Theses and Dissertations NonPeerReviewed
Published: [Yogyakarta] : Universitas Gadjah Mada 2013
Subjects:
ETD
Online Access:https://repository.ugm.ac.id/125793/
http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=65971
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Summary:Thirst is a common symptom and disturbing for patient with heart failure. Many elderly patients with heart failure get severe thirst. Natural history of heart failure, pharmacologycal and non-pharmacologycal therapies could increase the thirst level. Low cardiac output and activation of neuro-hormonal system e.g. renin-angiotensin-aldosteron system, would stimulate the thirst center in hypothalamus. Correlations of thirst with ejection fraction and plasma sodium level in elderly with chronic heart failure have not been known yet. The aims of this study are to investigate the correlations of thirst with ejection fraction and plasma sodium level in elderly with chronic heart failure. Cross sectional design has been conducted on elderly patients (age of � 60 years) with heart failure of functional class of III-IV (based on NYHA criteria) in Department of Internal Medicine and Department of Cardiology, Dr. Sardjito General Hospital, Yogyakarta. Measurement of thirst was done using VAS score, while the investigation of ejection fraction was performed using echocardiography. Characteristics of subjects were presented in the average and standard deviation values. Correlations between thirst with ejection fraction and plasma sodium level were analyzed by using Pearson correlation test with p < 0.05 considered to be significant. There were 30 subjects, 63.3% male, median of age of 69.5 years. The average of thirst value was 63.67±17.5 mm and the ejection fraction was 41.93±15.5%. The average of plasma sodium level and plasma osmolality were respectively 139.7±4.1 mmol/l and 296.4±10.1 mOsm/kg. Pearson correlation test has revealed weak negative correlation of thirst and ejection fraction (r=-0.314, p=0.091). On the other hand, there was no correlation between thirst and plasma sodium level (r=-0.04 p=0.833).