Effect of occupational aluminum exposure on cognitive function among informal aluminum foundry industry workers

• المؤلفون الرئيسيون: Silvia, Nelmi, Sutomo, Adi Heru, Astuti, Indwiani
• التنسيق: مقال PeerReviewed
• اللغة: English
• منشور في: Sanglah General Hospital 2022
• الموضوعات: Nursing; Public Health and Health Services
• الوصول للمادة أونلاين: https://repository.ugm.ac.id/284450/1/Sutomo_KKMK.pdf; https://repository.ugm.ac.id/284450/; https://balimedicaljournal.org/index.php/bmj/article/view/3483; https://doi.org/10.15562/bmj.v11i2.3483
• المؤسسة: Universitas Gadjah Mada

Background: Occupational exposure to aluminium can potentially cause health problems for workers in the aluminium foundry industry, which might associate with cognitive impairment. However, studies in the informal aluminium foundry industry are still very limited. This study aimed to determine the relationship between aluminium exposure and cognitive impairment in informal aluminium foundry workers. Methods: This study used a cross sectional design with logistic regression analysis. Seventy-nine workers in the informal aluminium foundry industry participated in this study. Aluminium in urine was measured using Inductively Coupled Plasma-Mass Spectrometry (ICP-MS). Cognitive function was measured using the Montreal Cognitive Assessment-Indonesian version (MoCA-Ina) instrument. Results: A total of 69.6% of the subjects experienced cognitive impairment. There was a statistically significant relationship between urinary aluminium levels and cognitive impairment. Multivariate logistic regression analysis showed that urinary aluminium levels (adjusted odds ratio (aOR) = 6.550; 95% confidence interval (CI) = 1.281-33.499) and length of education (aOR = 16.885; 95% CI = 2.042 – 139.604) were associated with cognitive impairment, with cut-off value set at 45.985 µg/L. Other results showed that workers with less than 7 years of formal education have a 16.885 times higher risk of experiencing cognitive impairment. Conclusion: Workers with urinary aluminium levels ≥45.985µg/L and formal education fewer than 7 years have a higher risk of having cognitive impairment. Regular bio-monitoring of workers’ urinary aluminium levels and adequate aluminium exposure control efforts are needed to prevent cognitive impairment in informal aluminium foundry workers.