MPTP- induced BALB/C mice recapitulate compensatory Parkinson’s-like motor features

• Main Authors: Musa Mustapha, Che Norma Mat Taib, Sharida Fakurazi, Mohamad Aris Mohd Moklas
• Format: Article
• Language: English
• Published: Penerbit Universiti Kebangsaan Malaysia 2024
• Online Access: http://journalarticle.ukm.my/23597/1/SMS%205.pdf; http://journalarticle.ukm.my/23597/; https://www.ukm.my/jsm/english_journals/vol53num1_2024/contentsVol53num1_2024.html
• Institution: Universiti Kebangsaan Malaysia

This study aimed to assess motor responses and associated pathological changes caused by MPTP neurotoxicity in Balb/c mice. Male mice (13 weeks old, 25-30 g) were divided into four groups and received intraperitoneal injections of normal saline or different doses of MPTP-HCl for five consecutive day...