Moelcular characterization of the promoter region of the nuclear factor Kappa-B Subunit 1 (NFKB1) gene; Towards its involvement in susceptibility to obesity in Malay obese attributes

• Main Authors: Atif, Amin Baig, Ahmad Zubaidi, A.latif, Nordin, Simbak, Tengku Mohammad Ariff, Raja Hussin
• Format: Article
• Language: English
• Published: 2017
• Subjects: R Medicine (General)
• Online Access: http://eprints.unisza.edu.my/5979/1/FH02-FP-18-13169.pdf; http://eprints.unisza.edu.my/5979/
• Institution: Universiti Sultan Zainal Abidin

The nuclear factor kappa-B subunit 1 (NFKB1) gene at 4q24 encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of t...