Acute liver failure secondary to paracetamol toxicity in a malnourished patient
Paracetamol has been most widely used as an antipyretic and analgesia medication worldwide as it is readily available at over-the-counter pharmacies and stores. The drug is considered safe at the usual therapeutic dose (4000 mg in 24 hours). Paracetamol overdose is known to cause drug-induced liver...
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| Main Authors: | , |
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| Format: | Proceeding Paper |
| Language: | English English |
| Published: |
2023
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/107643/18/107643_Acute%20liver%20failure%20secondary%20to%20paracetamol%20toxicity.pdf http://irep.iium.edu.my/107643/19/107643_Acute%20liver%20failure%20secondary%20to%20paracetamol%20toxicity_letter.pdf http://irep.iium.edu.my/107643/ https://www.msic.org.my/asmic.html |
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| Institution: | Universiti Islam Antarabangsa Malaysia |
| Language: | English English |
| Summary: | Paracetamol has been most widely used as an antipyretic and analgesia medication worldwide as it is readily available at over-the-counter pharmacies and stores. The drug is considered safe at the usual therapeutic dose (4000 mg in 24 hours). Paracetamol overdose is known to cause drug-induced liver injury and acute liver injury(ALI) and has been recognized since 1966 to cause fatal and nonfatal hepatic necrosis. There were few cases of ALI with therapeutic doses in susceptible individuals (for example, co-existing liver disease). We present a case of acute liver failure in a nontoxic dose of paracetamol in a malnourished cancer patient. |
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