Exploration of the main active metabolites from Tinospora crispa (L.) Hook. f. & Thomson stem as insulin sensitizer in L6.C11 skeletal muscle cell by integrating in vitro, metabolomics, and molecular docking

• Main Authors: Zuhri, Ummu Mastna, Yuliana, Nancy Dewi, Fadilah, Fadilah, Erlina, Linda, Purwaningsih, Erni Hernawati, Khatib, Alfi
• Format: Article
• Language: English; English
• Published: Elsevier 2024
• Subjects: RS Pharmacy and materia medica
• Online Access: http://irep.iium.edu.my/108772/7/108772_Exploration%20of%20the%20main%20active%20metabolites.pdf; http://irep.iium.edu.my/108772/8/108772_Exploration%20of%20the%20main%20active%20metabolites_Scopus.pdf; http://irep.iium.edu.my/108772/; https://www.sciencedirect.com/science/article/abs/pii/S0378874123011662
• Institution: Universiti Islam Antarabangsa Malaysia

Ethnopharmacological relevance: Tinospora crispa (L.) Hook. f. & Thomson stem (TCS) has long been used as folk medicine for the treatment of diabetes mellitus. Previous study revealed that TCS possesses multi-ingredients and multi-targets characteristic potential as insulin sensitizer activity....