Molecular docking studies of phytochemicals from Curcuma longa against trehalose-6-phosphate phosphatases of pathogenic microbes

• Main Authors: Johari, Nurul Anis, Azmihan, Adam, Abdullah, Mohamad Zakkirun, Bakar, Latifah Munirah
• Format: Article
• Language: English; English
• Published: Malaysian Institute of Chemistry 2024
• Subjects: QH301 Biology; QR Microbiology; RS Pharmacy and materia medica; TP248.13 Biotechnology
• Online Access: http://irep.iium.edu.my/114904/1/114904_Molecular%20docking%20studies.pdf; http://irep.iium.edu.my/114904/7/114904_Molecular%20docking%20studies_SCOPUS.pdf; http://irep.iium.edu.my/114904/; https://ikm.org.my/publications/malaysian-journal-of-chemistry/view-abstract.php?abs=J0052-97dd897
• Institution: Universiti Islam Antarabangsa Malaysia

Trehalose-6-phosphate phosphatases (TPP) are crucial enzymes used by pathogenic microbes for trehalose sugar biosynthesis, which is later beneficial for infection and proliferation. Therefore, inhibition of TPP proteins becomes the main focus for combating pathogenic microbial infection. This study...