COX-2 inhibitors: a potential target for drug therapy in the management of colorectal cancer

• Main Authors: Ryan, A R, Rosita, A R, Khalid, Kamarul Ariffin, Qureshi, Akhtar
• Format: Article
• Language: English
• Published: Malaysian Medical Association 1999
• Subjects: R Medicine (General)
• Online Access: http://irep.iium.edu.my/23984/1/COX-2_Inhibitors_-_A_Potential_Target_for_Drug_Therapy_in_the_Management_of_Colorectal_Cancer.pdf; http://irep.iium.edu.my/23984/; http://www.e-mjm.org/index.html
• Institution: Universiti Islam Antarabangsa Malaysia

Colorectal cancer is currently the third most common cancer in Malaysia. Elevated expression of COX-2, an induced cyclooxygenase isoenzyme, has been seen in colonic adenomas and colorectal carcinoma. There is evidence that inhibition of this COX-2 can decrease the risk of colorectal cancer. Selectiv...