Impact of chitosan composites and chitosan nanoparticle composites on various drug delivery systems: a review
Chitosan is a promising biopolymer for drug delivery systems. Because of its beneficial properties, chitosan is widely used in biomedical and pharmaceutical fields. In this review, we summarize the physicochemical and drug delivery properties of chitosan, selected studies on utilization of chitos...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English English |
| Published: |
National Laboratories of Foods and Drugs
2015
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/40787/4/Impact_of_chitosan_composites_and_chitosan.pdf http://irep.iium.edu.my/40787/7/40787_Impact%20of%20chitosan%20composites%20and%20chitosan_scopus.pdf http://irep.iium.edu.my/40787/ https://ac.els-cdn.com/S1021949814001410/1-s2.0-S1021949814001410-main.pdf?_tid=be55bdd8-049e-11e8-acb9-00000aacb362&acdnat=1517194228_89261db006868eca95b725174c53bc95 |
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| Institution: | Universiti Islam Antarabangsa Malaysia |
| Language: | English English |
| Summary: | Chitosan is a promising biopolymer for drug delivery systems. Because of its beneficial
properties, chitosan is widely used in biomedical and pharmaceutical fields. In this review,
we summarize the physicochemical and drug delivery properties of chitosan, selected
studies on utilization of chitosan and chitosan-based nanoparticle composites in various
drug delivery systems, and selected studies on the application of chitosan films in both
drug delivery and wound healing. Chitosan is considered the most important polysaccharide
for various drug delivery purposes because of its cationic character and primary
amino groups, which are responsible for its many properties such as mucoadhesion,
controlled drug release, transfection, in situ gelation, and efflux pump inhibitory properties
and permeation enhancement. This review can enhance our understanding of drug delivery
systems particularly in cases where chitosan drug-loaded nanoparticles are applied. |
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