A novel animal model for subcutaneous soft tissue infection

• Main Authors: Zulaziz, Natasha, N. , Himeno, H. , Miyazaki, D. , Saitoh, Noor Azmi, Azran Azhim, Y. , Morimoto
• Format: Article
• Language: English
• Published: J-STAGE 2014
• Subjects: RZ Other systems of medicine; TP248.13 Biotechnology
• Online Access: http://irep.iium.edu.my/44152/1/A_Novel_Animal_Model_for_Subcutaneous_Soft_Tissue_Infection.pdf; http://irep.iium.edu.my/44152/; https://www.jstage.jst.go.jp/article/jsmbe/52/Supplement/52_O-285/_article; http://doi.org/10.11239/jsmbe.52.O-285
• Institution: Universiti Islam Antarabangsa Malaysia

In order to simultaneously monitor neutrophil migration in vivo during inflammation, we developed a novel animal model for subcutaneous soft tissue infection using transgenic mouse bearing fluorescence-positive neutrophils and bioluminescent methicillin-resistant Staphylococcus aureus (MRSA). Metho...