Coeliac disease: immunogenicity studies of barley hordein and rye secalin-derived peptides

• Main Authors: Abdul Wahab, Widya, Šuligoj, Tanja, Ellis, Julia H., Côrtez-Real, Beatriz, Ciclitira, Paul Jonathan
• Format: Article
• Language: English; English
• Published: Wiley-Blackwell 2016
• Subjects: Q Science (General)
• Online Access: http://irep.iium.edu.my/54747/9/54747_Coeliac%20disease_article.pdf; http://irep.iium.edu.my/54747/2/54747_Coeliac%20disease_SCOPUS.pdf; http://irep.iium.edu.my/54747/; http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1365-2613
• Institution: Universiti Islam Antarabangsa Malaysia

Coeliac disease (CD) is an inflammatory disorder of the small intestine. It includes aberrant adaptive immunity with presentation of CD toxic gluten peptides by HLA-DQ2 or DQ8 molecules to gluten-sensitive T cells. A ω-gliadin/C-hordein peptide (QPFPQPEQPFPW) and a rye-derived secalin peptide (QPFPQ...