Principal component analysis application on flavonoids characterization

• Main Authors: Che Noh, Che Hafizah, Mohamed Azmin, Nor Fadhillah, Amid, Azura
• Format: Article
• Language: English
• Published: Thomson Reuters 2017
• Subjects: TP155 Chemical engineering; TP248.13 Biotechnology
• Online Access: http://irep.iium.edu.my/59897/1/ASTESJ_PCA%20Application%20on%20Flavonoids%20Characterization.pdf; http://irep.iium.edu.my/59897/; https://astesj.com/v02/i03/p56/
• Institution: Universiti Islam Antarabangsa Malaysia

Flavonoid is one of the bioactive compounds that are currently used in pharmaceutical and medicinal industries due to their health benefit. The focus of current research is mainly on the extraction and isolation of bioactive compounds; however non to date has explored on the identification of flavonoids classes under the Fourier Transform Infrared spectroscopy (FTIR). This gap presents an opportunity for the application of statistical analysis which can identify the distinct wavenumbers range of flavone, flavanone and flavonol for their characterization in the FTIR spectrum. Development of algorithm based on principal component analysis (PCA) for the analysis and identification of flavonoids classes based on FTIR spectrum was introduced. Based on the results, five wavenumbers ranges have been identified as the distinct characteristics of flavonol, flavone and flavanone hence used for their identification.