Two-dimensional electrophoresis protein profiles of HL-60 and CCRF-CEM cell lines treated with epigenetic modification drugs

• Main Authors: Sudin, Aziee, Mohd Yassim, Haiyuni, Mohamed Yusof, Shafini, Shamsuddin, Shaharum, Abdul Wahab, Ridhwan, Johan, Muhammad Farid
• Format: Article
• Language: English; English
• Published: Malaysian Society For Molecular Biology & Biotechnology 2019
• Subjects: RM300 Drugs and their action
• Online Access: http://irep.iium.edu.my/73822/7/73822%20Two-dimensional%20electrophoresis%20protein%20profiles.pdf; http://irep.iium.edu.my/73822/8/73822%20Two-dimensional%20electrophoresis%20protein%20profiles%20SCOPUS.pdf; http://irep.iium.edu.my/73822/; http://www.msmbb.my/images/publication/volume_27/issue_3/02-Sudin-et-al.pdf
• Institution: Universiti Islam Antarabangsa Malaysia

Leukemia is classified as a malignant disease of hematopoietic stem cells (HSCs) that fails in cell differentiation but preserve their self-renewal. It is caused by genetic alterations and epigenetic modifications resulting in the activation or inactivation of particular genes for transcription. Epi...