Combination of polymyxin B and Aquilaria malaccensis extract enhanced the killing and inhibited the growth of Acinetobacter baumannii and Klebsiella pneumoniae

• Main Authors: Nurul 'Izzati, Mohd Jihadi, Mahamad Maifiah, Mohd Hafidz, Nusaibah, Abdul Rahim, Abdullah Sani, Muhamad Shirwan, Hashim, Yumi Zuhanis Has-Yun, Khairunnisa, Mohd Kamal
• Format: Article
• Language: English
• Published: Malaysian Society for Microbiology 2022
• Subjects: QD Chemistry; QK Botany; QR Microbiology; RA643 Communicable Diseases and Public Health; RM300 Drugs and their action; RS403 Materia Medica-Pharmaceutical Chemistry
• Online Access: http://irep.iium.edu.my/96567/1/96567_%20Combination%20of%20polymyxin%20B%20and%20Aquilaria%20malaccensis%20extract.pdf; http://irep.iium.edu.my/96567/; http://mjm.usm.my/uploads/issues/1721/Formatted%20MJM-21-1241-Ready-colour.pdf; http://dx.doi.org/10.21161/mjm.211241
• Institution: Universiti Islam Antarabangsa Malaysia

Aims: Polymyxins are an important last-line treatment for infections caused by multidrug-resistant Gram-negative bacteria. Nonetheless, the emergence of polymyxin resistance and the limiting of polymyxin monotherapy urgently demands its optimisation. Aquilaria malaccensis (Agarwood) has been widely...