Targeting cyst wall is an effective strategy in improving the efficacy of marketed contact lens disinfecting solutions against Acanthamoeba castellanii cysts

• Main Authors: Abjani, Farhat, Khan, Naveed Ahmed *, Yousuf, Farzana Abubakar, Siddiqui, Ruqaiyyah Bano *
• Format: Article
• Language: English
• Published: Elsevier 2016
• Subjects: QR Microbiology
• Online Access: http://eprints.sunway.edu.my/623/1/ZZ%20Contact%20Lens%20and%20Anterior%20Eye.pdf; http://eprints.sunway.edu.my/623/; http://dx.doi.org/10.1016/j.clae.2015.11.004
• Institution: Sunway University

Acanthamoeba cysts are highly resistant to contact lens disinfecting solutions. Acanthamoeba cyst wall is partially made of 1,4 β-glucan (i.e., cellulose) and other complex polysaccharides making it a hardy shell that protects the resident amoeba. Here, we hypothesize that targeting the cyst wall st...