Response of cellular innate immunity to Cnidarian Pore-Forming toxins

• Main Authors: Yap, Wei Yuen *, Hwang, Jung Shan *
• Format: Article
• Language: English
• Published: MDPI 2018
• Subjects: RM Therapeutics. Pharmacology
• Online Access: http://eprints.sunway.edu.my/948/1/Hwang%20Jung%20Response%20Molecules%20Review%202018.pdf; http://eprints.sunway.edu.my/948/; http://doi.org/10.3390/molecules23102537
• Institution: Sunway University

A group of stable, water-soluble and membrane-bound proteins constitute the pore forming toxins (PFTs) in cnidarians. They interact with membranes to physically alter the membrane structure and permeability, resulting in the formation of pores. These lesions on the plasma membrane causes an imbalanc...