Mechanism of Aloe Emodin-Induced Apoptosis in ER+ - Breast Cancer Cells, MCF-7 / Indah Mohd Amin

• Main Author: Mohd Amin, Indah
• Format: Thesis
• Language: English
• Published: 2016
• Subjects: Breast. Mammary glands; Diseases of the breast
• Online Access: https://ir.uitm.edu.my/id/eprint/62199/1/62199.pdf; https://ir.uitm.edu.my/id/eprint/62199/
• Institution: Universiti Teknologi Mara

Aloe emodin, an anthraquinone exhibits higher cytotoxicity to hepatoma, prostate and cervical cancer cells through cell cycle arrest and apoptosis compared to normal cells. However, its underlying mechanism on ER+ -breast cancer cell death remains unclear. Therefore, this study was done to investiga...