CD4(+)CD25(hi)CD127(low) Regulatory T Cells Are Increased in Oral Squamous Cell Carcinoma Patients

• Main Authors: Lim, K.P., Chun, N.A.L., Ismail, S.M., Abraham, M.T., Yusoff, M.N., Zain, R.B., Ngeow, Wei Cheong
• Format: Article
• Language: English
• Published: Public Library of Science 2014
• Subjects: RK Dentistry
• Online Access: http://eprints.um.edu.my/11363/1/fetchObjectAttachment-libre.pdf; http://eprints.um.edu.my/11363/; http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0103975
• Institution: Universiti Malaya

Regulatory T cells (Tregs), a subset of CD4+ T cells plays a pivotal role in regulating the immune system. An increase in Treg numbers enables cancer progression by dampening the immune system and allowing tumor cells to evade immune detection and destruction. An increase in Treg numbers and express...