Successful treatment of Candida albicans endocarditis in a child with leukemia--a case report and review of the literature

Candida species is now being increasingly recognised as an important cause of endocarditis especially in immunocompromised patients. A case of Candida albicans endocarditis in a child with acute lymphoblastic leukemia (ALL) is reported. The child did not have a central venous catheter at any time. T...

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Bibliographic Details
Main Authors: Ariffin, H., Ariffin, W., Tharam, S., Omar, A., de Bruyne, J., Lin, H.P.
Format: Article
Published: Stamford Publishing Pte Ltd / Singapore Medical Association 1999
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Online Access:http://eprints.um.edu.my/1517/
http://www.ncbi.nlm.nih.gov/pubmed/10572495
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Institution: Universiti Malaya
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Summary:Candida species is now being increasingly recognised as an important cause of endocarditis especially in immunocompromised patients. A case of Candida albicans endocarditis in a child with acute lymphoblastic leukemia (ALL) is reported. The child did not have a central venous catheter at any time. Treatment consisted of intravenous amphotericin B and fluconazole for 3 weeks followed by oral fluconazole for 2 weeks. No surgical resection was necessary. We highlight here the importance of echocardiography in the management of prolonged febrile neutropenia and discuss the dilemma of continuing chemotherapy in such patients.