Ultraviolet-visible study on acid-base equilibria of aporphine alkaloids with antiplasmodial and antioxidant activities from Alseodaphne corneri and Dehaasia longipedicellata

• Main Authors: Zahari, Azeana, Ablat, A., Omer, N., Nafiah, M.A., Sivasothy, Y., Mohamad, Jamaludin, Khan, M.N., Awang, Khalijah
• 格式: Article
• 出版: Nature Publishing Group 2016
• 主題: Q Science (General); QD Chemistry
• 在線閱讀: http://eprints.um.edu.my/18725/; http://dx.doi.org/10.1038/srep21517

The UV-vis spectra of isocorydine 1, norisocorydine 2 and boldine 3 were studied in 2% v/v acetonitrile, at constant ionic strength (0.1 M NaCl, 35 degree Celsius). The pKa values of isocorydine 1 and norisocorydine 2 were 11.75 and 12.07, respectively. Boldine 3 gave a pKa value of 9.16 and 10.44....