Activation of Akt and the signaling of phosphorylated Akt in the L5 dorsal root ganglia in aging rats

Introduction Protein kinase B (PKB)/Akt is a kinase that is responsive towards insulin-like growth factor (IGF-1) and nerve growth factor (NGF). Detected in the cytosol, Akt is activated by phosphorylation at Thr308/Ser473 residue. The phosphorylated Akt (pAkt) is translocated into the nucleus via t...

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Main Authors: Yon, H.M., Naidu, M.
Format: Article
Published: Elsevier 2017
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Online Access:http://eprints.um.edu.my/18908/
http://dx.doi.org/10.1016/j.jasi.2017.05.009
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Institution: Universiti Malaya