Facile Intramolecular Cyclization of N -(2-Hydroxybenzoyl)hydrazones to N ,N′ -Diacetyl Benzo-1,3,4-oxadiazepine Derivatives

A facile synthesis of seven-membered benzo-1,3,4-oxadiazepines through one-step intramolecular cyclization of N-(2-hydroxybenzoyl)hydrazones has been established. The catalytic and substituent effects on the reactivity of this intramolecular cyclization were investigated. Through this strategy, a se...

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Main Authors: Chan, Pei Qie, Lee, Yean Kee, Abd Rahman, Noorsaadah
Format: Article
Published: Wiley-VCH Verlag 2018
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Online Access:http://eprints.um.edu.my/22279/
https://doi.org/10.1002/ajoc.201800014
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spelling my.um.eprints.222792019-09-06T06:35:34Z http://eprints.um.edu.my/22279/ Facile Intramolecular Cyclization of N -(2-Hydroxybenzoyl)hydrazones to N ,N′ -Diacetyl Benzo-1,3,4-oxadiazepine Derivatives Chan, Pei Qie Lee, Yean Kee Abd Rahman, Noorsaadah Q Science (General) QD Chemistry A facile synthesis of seven-membered benzo-1,3,4-oxadiazepines through one-step intramolecular cyclization of N-(2-hydroxybenzoyl)hydrazones has been established. The catalytic and substituent effects on the reactivity of this intramolecular cyclization were investigated. Through this strategy, a series of benzo-1,3,4-oxadiazepine derivatives were prepared (with yields up to 83 %). Wiley-VCH Verlag 2018 Article PeerReviewed Chan, Pei Qie and Lee, Yean Kee and Abd Rahman, Noorsaadah (2018) Facile Intramolecular Cyclization of N -(2-Hydroxybenzoyl)hydrazones to N ,N′ -Diacetyl Benzo-1,3,4-oxadiazepine Derivatives. Asian Journal of Organic Chemistry, 7 (4). pp. 707-710. ISSN 2193-5807 https://doi.org/10.1002/ajoc.201800014 doi:10.1002/ajoc.201800014
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic Q Science (General)
QD Chemistry
spellingShingle Q Science (General)
QD Chemistry
Chan, Pei Qie
Lee, Yean Kee
Abd Rahman, Noorsaadah
Facile Intramolecular Cyclization of N -(2-Hydroxybenzoyl)hydrazones to N ,N′ -Diacetyl Benzo-1,3,4-oxadiazepine Derivatives
description A facile synthesis of seven-membered benzo-1,3,4-oxadiazepines through one-step intramolecular cyclization of N-(2-hydroxybenzoyl)hydrazones has been established. The catalytic and substituent effects on the reactivity of this intramolecular cyclization were investigated. Through this strategy, a series of benzo-1,3,4-oxadiazepine derivatives were prepared (with yields up to 83 %).
format Article
author Chan, Pei Qie
Lee, Yean Kee
Abd Rahman, Noorsaadah
author_facet Chan, Pei Qie
Lee, Yean Kee
Abd Rahman, Noorsaadah
author_sort Chan, Pei Qie
title Facile Intramolecular Cyclization of N -(2-Hydroxybenzoyl)hydrazones to N ,N′ -Diacetyl Benzo-1,3,4-oxadiazepine Derivatives
title_short Facile Intramolecular Cyclization of N -(2-Hydroxybenzoyl)hydrazones to N ,N′ -Diacetyl Benzo-1,3,4-oxadiazepine Derivatives
title_full Facile Intramolecular Cyclization of N -(2-Hydroxybenzoyl)hydrazones to N ,N′ -Diacetyl Benzo-1,3,4-oxadiazepine Derivatives
title_fullStr Facile Intramolecular Cyclization of N -(2-Hydroxybenzoyl)hydrazones to N ,N′ -Diacetyl Benzo-1,3,4-oxadiazepine Derivatives
title_full_unstemmed Facile Intramolecular Cyclization of N -(2-Hydroxybenzoyl)hydrazones to N ,N′ -Diacetyl Benzo-1,3,4-oxadiazepine Derivatives
title_sort facile intramolecular cyclization of n -(2-hydroxybenzoyl)hydrazones to n ,n′ -diacetyl benzo-1,3,4-oxadiazepine derivatives
publisher Wiley-VCH Verlag
publishDate 2018
url http://eprints.um.edu.my/22279/
https://doi.org/10.1002/ajoc.201800014
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