Significant pulmonary disease burden in treatment resistant disseminated cryptococcal infection: A case report
Cryptococcus neoformans causes severe disseminated infection in immunocompromised individuals. We report a case of an immunocompetent adult male who presented with treatment-resistant central nervous system manifestations and significant pulmonary disease burden. Hematology and lumbar puncture were...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Published: |
Springer Verlag
2017
|
| Subjects: | |
| Online Access: | http://eprints.um.edu.my/22842/ https://doi.org/10.1007/s12055-017-0545-7 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Institution: | Universiti Malaya |
| Summary: | Cryptococcus neoformans causes severe disseminated infection in immunocompromised individuals. We report a case of an immunocompetent adult male who presented with treatment-resistant central nervous system manifestations and significant pulmonary disease burden. Hematology and lumbar puncture were positive, aided by computerized tomography-guided histological confirmation. Despite medical therapy, there was inadequate resolution, and surgical resection was performed. On follow-up, investigations showed complete resolution, and the patient has remained disease-free at 5 years. This highlights the importance of looking for other sites in resistant cryptococcal meningitis and the value of cardiothoracic intervention for slowly resolving pulmonary cryptococcomas. |
|---|