Tocotrienols Modulate Breast Cancer Secretomes and Affect Cancer-Signaling Pathways in MDA-MB-231 Cells: A Label-Free Quantitative Proteomic Analysis

• Main Authors: Ramdas, Premdass, Radhakrishnan, Ammu Kutty, Abdu Sani, Asmahani Azira, Abdul-Rahman, Puteri Shafinaz
• Format: Article
• Published: Taylor & Francis 2019
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/23684/; https://doi.org/10.1080/01635581.2019.1607407
• Institution: Universiti Malaya

Tocotrienols (T3), a family of vitamin E, are reported to possess potent anti-cancer effects but the molecular mechanisms behind these effects still remain unclear. The aim of this study was to investigate how T3 exert anti-cancer effects on MDA-MB-231 human breast cancer cells. The MDA-MB-231 cells...