Exposure to high-fat style diet induced renal and liver structural changes, lipid accumulation and inflammation in intact and ovariectomized female rats

• Main Authors: Sucedaram, Yamuna, Johns, Edward James, Husain, Ruby, Sattar, Munavvar Abdul, Abdulla, Mohammed H., Nelli, Giribabu, Rahim, Nur Syahrina, Khalilpourfarshbafi, Manizheh, Abdullah, Nor Azizan
• Format: Article
• Published: Dove Medical Press Ltd 2021
• Subjects: QR180 Immunology
• Online Access: http://eprints.um.edu.my/34278/
• Institution: Universiti Malaya

Purpose: We hypothesized that low estrogen levels aggravate obesity-related complications. Diet-induced obesity can cause distinct pathologies, including impaired glucose tolerance, inflammation, and organ injury that leads to fatty liver and chronic kidney diseases. To test this hypothesis, ovariec...