An in vitro alpha-neurotoxin-nAChR binding assay correlates with lethality and in vivo neutralization of a large number of elapid neurotoxic snake venoms from four continents
The aim of this study was to develop anin vitroassay for use in place ofin vivoassays of snake venom lethality and antivenom neutralizing potency. A novelin vitroassay has been developed based on the binding of post-synaptically acting alpha-neurotoxins to nicotinic acetylcholine receptor (nAChR), a...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Published: |
Public Library of Science
2020
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| Subjects: | |
| Online Access: | http://eprints.um.edu.my/36525/ |
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| Institution: | Universiti Malaya |