Activation of intrinsic apoptosis and G1 cell cycle arrest by a triazole precursor, N-(4-chlorophenyl)-2-(4-(3,4,5-trimethoxybenzyloxy)benzoyl)-hydrazinecar bothioamide in breast cancer cell line

• Main Authors: Arulnathan, Stephanie B., Leong, Kok Hoong, Ariffin, Azhar, Kareem, Huda S., Cheah, Kevin K. H.
• Format: Article
• Published: Bentham Science Publishers 2020
• Subjects: QD Chemistry; RS Pharmacy and materia medica
• Online Access: http://eprints.um.edu.my/37982/
• Institution: Universiti Malaya

Background: Oxadiazoles, triazoles, and their respective precursors have been shown to exhibit various pharmacological properties, namely antitumour activities. Cytotoxic activity was reported for these compounds in various cancer cell lines. Aim and objectives: In this study, we aim at investigatin...