Neuroprotective activities of new monoterpenoid indole alkaloid from nauclea officinalis

• Main Authors: Liew, Sook Yee, Mak, Wen Qi, Thew, Hin Yee, Khaw, Kooi Yeong, Hazni, Hazrina, Litaudon, Marc, Awang, Khalijah
• Format: Article
• Published: MDPI 2023
• Subjects: Q Science (General); QD Chemistry
• Online Access: http://eprints.um.edu.my/38524/
• Institution: Universiti Malaya

Phytochemical investigation on the bark of Nauclea officinalis led to the isolation of a new monoterpenoid indole alkaloid, nauclediol. The structure of the compound was identified through extensive spectroscopic analysis. Nauclediol displayed cholinesterase-inhibitory activities towards AChE and BC...