Design, synthesis and anticolorectal cancer activity of 2- bromoalkoxyanthraquinones

Design, synthesis and anticolorectal cancer activity of 2- bromoalkoxyanthraquinones

The impact of alkoxy chain length and the presence of a 1-hydroxy group in synthesised 2-bromoalkoxyanthraquinones was evaluated against HCT116, HT29, and CCD841 CoN cell lines. Molecular docking was employed to elucidate the interactions between these compounds and potential p53 and KRAS targets...

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Bibliographic Details
Main Authors: Lee, Yean Kee, Nurhaliza, Wati Mekzali, Cheok, Wui Chee, Iskandar, Abdullah, Nurshamimi, Nor Rashid, Vannajan, Sanghiran Lee, Rozana, Othman, Najihah, Mohd Hashim, Chin, Fei Chee
Format: Conference or Workshop Item
Language:English
English
Published: 2024
Subjects:
Q Science (General)
QD Chemistry
Online Access:http://eprints.um.edu.my/45060/1/Lee%20Yean%20Kee-ACP2023-Abstract.pdf
http://eprints.um.edu.my/45060/2/Lee%20Yean%20Kee-ACP2023-Poster.pdf
http://eprints.um.edu.my/45060/
https://icceoca16.sg/
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Institution: Universiti Malaya
Language: English
English

Internet

http://eprints.um.edu.my/45060/1/Lee%20Yean%20Kee-ACP2023-Abstract.pdf
http://eprints.um.edu.my/45060/2/Lee%20Yean%20Kee-ACP2023-Poster.pdf
http://eprints.um.edu.my/45060/
https://icceoca16.sg/

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