Epitope mapping and functional characterization of monoclonal antibodies against the tip-localized adhesions of CFA/I, CS17 and CS2 class 5 fimbriae of enterotoxigenic Escherichia coli

• Main Author: Sakina, Shahabudin
• Format: Thesis
• Language: English
• Published: 2013
• Subjects: T Technology (General); TP Chemical technology
• Online Access: http://umpir.ump.edu.my/id/eprint/13510/1/BIOTECHNOLOGY-%20SAKINA%20SHAHABUDIN.PDF; http://umpir.ump.edu.my/id/eprint/13510/
• Institution: Universiti Malaysia Pahang

Enterotoxigenic Escherichia coIi(ETEC), a common cause of diarrhea among children in developing countries and in travelers, adheres to human small intestine via colonization factors (CFs) and secretes enterotoxins. Eight genetically related Class 5 fimbriae are prevalent ETEC CFs. Each is composed o...