Potential Role of Oxidative Stress-Induced Apoptosis in Mediating Chromosomal Rearrangements in Nasopharyngeal Carcinoma

• Main Authors: Tan, Sang-Nee, Sim, Sai-Peng, Khoo, Alan S.B.
• Format: E-Article
• Language: English
• Published: Biomed Central 2016
• Subjects: QH301 Biology; QH426 Genetics; RB Pathology
• Online Access: http://ir.unimas.my/id/eprint/12300/1/Potential%20role%20of%20oxidative%20stress%E2%80%91induced%20apoptosis%20in%20mediating%20chromosomal%20%28abstract%29.pdf; http://ir.unimas.my/id/eprint/12300/; http://cellandbioscience.biomedcentral.com/
• Institution: Universiti Malaysia Sarawak

Abstract Background Genetic aberrations have been identified in nasopharyngeal carcinoma (NPC), however, the underlying mechanism remains elusive. There are increasing evidences that the apoptotic nuclease caspase-activated deoxyribonuclease (CAD) is one of the players leading to translocation in...