Efficient ecofriendly synthesis of pyrazole acryloyl analogs by amino acid catalysis

• Main Authors: Chaudhry, F., Asif, N., Shafqat, S.S., Khan, A.A., Munawar, M.A., Khan, M.A.
• Format: Article
• Language: English
• Published: Taylor and Francis Inc. 2016
• Subjects: TS Manufactures
• Online Access: http://ir.unimas.my/id/eprint/12506/1/Efficient%20ecofriendly%20-%20Copy.pdf; http://ir.unimas.my/id/eprint/12506/; https://www.scopus.com/inward/record.uri?eid=2-s2.0-84971247630&partnerID=40&md5=46af5ce0a7c4f874ac025ca3bd02af86
• Institution: Universiti Malaysia Sarawak

An easy and effective green approach of Knoevenagel condensation and arylidene formation with the substrates involves pyrazole-3-carbaldehydes and active methylenes under catalytic action of glycine (the simplest amino acid) in dimethylsulfoxide. These reactions were successfully carried out at room...