Mefenamic acid in combination with ribavirin shows significant effects in reducing chikungunya virus infection in vitro and in vivo

• Main Authors: Rothan, H.A., Bahrani, H., Abdulrahman, A.Y., Mohamed, Z., Teoh, T.C., Othman, S., Rashid, N.N., Rahman, N.A., Yusof, R.
• Format: Article
• Language: English
• Published: 2017
• Subjects: Meclofenamic; Acidmefenamic; Acidribavirin
• Institution: Universiti Tenaga Nasional

Chikungunya virus (CHIKV) infection is a persistent problem worldwide due to efficient adaptation of the viral vectors, Aedes aegypti and Aedes albopictus mosquitoes. Therefore, the absence of effective anti-CHIKV drugs to combat chikungunya outbreaks often leads to a significant impact on public he...