Roles of sodium hydrogen exchanger (NHE1) and anion exchanger (AE2) across chondrocytes plasma membrane during longitudinal bone growth

• Main Authors: Abdul Abubakar, Adamu, Ali, Ahmed Khalaf, Mohammed Ibrahim, Sahar, Handool, Kareem Obayes, Khan, Mohammad Shuaib, Mohamed Mustapha, Noordin, Tengku Ibrahim, Tengku Azmi, Kaka, Ubedullah, Mohamad Yusof, Loqman
• Format: Article
• Published: MDPI 2022
• Online Access: http://psasir.upm.edu.my/id/eprint/103121/; https://www.mdpi.com/2077-0375/12/7/707
• Institution: Universiti Putra Malaysia

Mammalian long bone growth occurs through endochondral ossification, majorly regulated by the controlled enlargement of chondrocytes at the growth plate (GP). This study aimed to investigate the roles of Na+/H+ (sodium hydrogen exchanger (NHE1)) and HCO3− (anion exchanger [AE2]) during longitudinal...