A case of Acute Transverse Myelopathy following Measles-Mumps-Rubella (MMR) vaccination in Malaysia.

Objective : To describe the clinical course case of Acute Transverse Myelopathy following an MMR vaccination and the review the literature regarding association of transverse myelitis and vaccination. Method: Case report Results: A 1-year old healthy Chinese boy presented with 5 days history...

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Bibliographic Details
Main Author: Mohd Fakharuddin, Mohd. Feizel Alsiddiq
Format: Conference or Workshop Item
Online Access:http://psasir.upm.edu.my/id/eprint/27614/
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Institution: Universiti Putra Malaysia
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Summary:Objective : To describe the clinical course case of Acute Transverse Myelopathy following an MMR vaccination and the review the literature regarding association of transverse myelitis and vaccination. Method: Case report Results: A 1-year old healthy Chinese boy presented with 5 days history of fever, coryzal symptoms and acute bilateral symmetrical lower limb weakness with urinary incontinence 4 days following his first Measles-Mumps-Rubella (MMR) vaccination. Examination revealed an alert child with bilateral flaccid symmetrical weakness of his lower limbs. His MRI findings, nerve conduction study and other relevant investigations are discussed. The clinical progress following treatment with review of all reported systemic and neurologic adverse reactions to MMR vaccination since its introduction in Malaysia are reviewed. Conclusion: Acute transverse myelitis following MMR vaccination is extremely rare and this is the first reported case in Malaysia.