Pharmacologically antagonizing the CXCR4-CXCL12 chemokine pathway with AMD3100 inhibits sunlight-induced skin cancer
One way sunlight causes skin cancer is by suppressing anti-tumor immunity. A major mechanism involves altering mast cell migration via the C-X-C motif chemokine receptor 4–C-X-C motif chemokine ligand 12 (CXCR4-CXCL12) chemokine pathway. We have discovered that pharmacologically blocking this pathwa...
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| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2014
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| Online Access: | http://psasir.upm.edu.my/id/eprint/34895/1/Pharmacologically%20antagonizing%20the%20CXCR4.pdf http://psasir.upm.edu.my/id/eprint/34895/ http://www.nature.com/jid/journal/v134/n4/abs/jid2013424a.html |
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| Institution: | Universiti Putra Malaysia |
| Language: | English |