State of the art of nanocrystals – special features, production, nanotoxicology aspects and intracellular delivery

• Main Authors: Muller, Rainer Helmut, Gohla, Sven H., Keck, Cornelia M.
• Format: Article
• Language: English
• Published: Elsevier 2011
• Online Access: http://psasir.upm.edu.my/id/eprint/40025/1/State%20of%20the%20art%20of%20nanocrystals.pdf; http://psasir.upm.edu.my/id/eprint/40025/; http://www.sciencedirect.com/science/article/pii/S0939641111000142
• Institution: Universiti Putra Malaysia

Drug nanocrystals are the latest, broadly introduced nanoparticulate carrier to the pharmaceutical market from the year 2000 onwards. The special features of nanocrystals for the delivery of poorly soluble drugs are briefly reviewed (saturation solubility, dissolution velocity, adhesiveness). The in...