Radiation cross-linked carboxymethyl sago pulp hydrogels loaded with ciprofloxacin: Influence of irradiation on gel fraction, entrapped drug and in vitro release

• Main Authors: Lam, Yi Lyn, Muniyandy, Saravanan, Kamaruddin, Hashim, Mansor, Ahmad, Janarthanan, Pushpamalar
• Format: Article
• Language: English
• Published: Elsevier 2015
• Online Access: http://psasir.upm.edu.my/id/eprint/46072/1/Radiation%20cross-linked%20carboxymethyl%20sago%20pulp%20hydrogels%20loaded%20with%20ciprofloxacin%20influence%20of%20irradiation%20on%20gel%20fraction%2C%20entrapped%20drug%20and%20in%20vitro%20release.pdf; http://psasir.upm.edu.my/id/eprint/46072/; https://www.sciencedirect.com/science/article/pii/S0969806X14003260
• Institution: Universiti Putra Malaysia

Carboxymethyl sago pulp (CMSP) with 0.4 DS, viscosity 184 dl/g and molecular weight 76,000 g/mol was synthesized from sago waste. 10 and 20% w/v solutions of CMSP were irradiated at 10–30 kGy to form hydrogels and were characterized by % gel fraction (GF). Irradiation of 20% CMSP using 25 kGy has pr...