Neuro-therapeutic benefits of Centella asiatica on some neurodegenerative diseases: a review
Medicinal herbalism has become popular because of its documented efficacy, synergistic interactions against complex conditions and lesser side effects. CA (CA) is a traditional Ayurveda medicine widely used in India, China, and Malaysia and across countries in south-eastern Asia for treating a range...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
RJPBCS
2017
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| Online Access: | http://psasir.upm.edu.my/id/eprint/62523/1/NEURO.pdf http://psasir.upm.edu.my/id/eprint/62523/ https://www.researchgate.net/publication/331356684_Neuro-therapeutic_Benefits_of_Centella_asiatica_on_Some_Neurodegenerative_Diseases_A_Review/link/5c7577ca458515831f728cbc/download |
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| Institution: | Universiti Putra Malaysia |
| Language: | English |
| Summary: | Medicinal herbalism has become popular because of its documented efficacy, synergistic interactions against complex conditions and lesser side effects. CA (CA) is a traditional Ayurveda medicine widely used in India, China, and Malaysia and across countries in south-eastern Asia for treating a range of diseases. The whole plant or its parts (leaf or roots) are used for medicinal purpose and its chemical constituents have been proven scientifically to have neuro-protective, wound healing, anti-inflammatory and antioxidants activities. In this review we have retrieved and evaluated available literatures on neuro-therapeutic properties of CA on neurotoxic and transgenic models of Alzheimer’s diseases (AD), Parkinson’s disease (PD) and Huntington’s disease (HD). The extract was found to have neuroprotective ability through modifying a key signaling pathways and events concerned with neuro-degeneration. Further research is required to discover more bioactive compounds of CA and their exact mode of action. |
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