Distribution of GSTM1 and GSTT1 polymorphisms among caucasians and the three major ethnic groups in Malaysia

• Main Author: Wan Rashidi, Wan Nooremira
• Format: Thesis
• Language: English
• Published: 2018
• Subjects: Glutathione Transferase; Structure - Activity Relationship
• Online Access: http://psasir.upm.edu.my/id/eprint/76283/1/FPSK%28M%29%202018%2018%20-%20IR.pdf; http://psasir.upm.edu.my/id/eprint/76283/
• Institution: Universiti Putra Malaysia

Glutathione S-transferases (GSTs) are the vital Phase II enzymes to detoxify carcinogens and reactive oxygen species in the body, which encoded by GST mu class 1 (GSTM1) and GST theta class 1 (GSTT1) genes. Polymorphism in the genes affects the enzyme expression and increases the susceptibility to d...