Induction of endoplasmic reticulum stress pathway by green tea epigallocatechin-3-gallate (EGCG) in colorectal cancer cells: activation of PERK/p-eIF2α/ATF4 and IRE1α

Epigallocatechin-3-gallate (EGCG) is the most abundant bioactive polyphenolic compound among the green tea constituents and has been identified as a potential anticancer agent in colorectal cancer (CRC) studies. This study was aimed to determine the mechanism of actions of EGCG when targeting the en...

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Bibliographic Details
Main Authors: Md Nesran, Zarith Nameyrra, Shafie, Nurul Husna, Ishak, Amirah Haziyah, Mohd Esa, Norhaizan, Ismail, Amin, Md Tohid, Siti Farah
Format: Article
Language:English
Published: Hindawi 2019
Online Access:http://psasir.upm.edu.my/id/eprint/80246/1/Induction%20of%20endoplasmic%20reticulum%20stress%20pathway%20by%20green%20tea.pdf
http://psasir.upm.edu.my/id/eprint/80246/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942794/
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Institution: Universiti Putra Malaysia
Language: English