ExlP induction of efficient RNAi loaded exosome production by stem cells:a novel tool for gene therapy.

Alteration of gene expression plays important roles in disease inception. Controlling the expression of diseases-related genes may be used as treatment modality. Regulation of gene expression through RNA interference (RNAi) by using shRNA is well-established. However, absence of appropriate delivery...

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Bibliographic Details
Main Author: A Ali, Syed
Format: Monograph
Published: Universiti Sains Malaysia 2016
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Online Access:http://eprints.usm.my/31826/
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Institution: Universiti Sains Malaysia
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Summary:Alteration of gene expression plays important roles in disease inception. Controlling the expression of diseases-related genes may be used as treatment modality. Regulation of gene expression through RNA interference (RNAi) by using shRNA is well-established. However, absence of appropriate delivery vehicles has impeded the development of RNAi into a viable therapeutic modality.